ABCD syndrome

ABCD syndrome is the acronym for albinism, black lock, cell migration disorder of the neurocytes of the gut and sensorineural deafness. It has been found to be caused by mutation in the endothelin B receptor gene (EDNRB). Read more here.

Hikikomori

Hikikomori (ひきこもり or 引き籠もり, Hikikomori?, lit. "pulling away, being confined", i.e., "acute social withdrawal") is a Japanese term to refer to the phenomenon of reclusive people who have chosen to withdraw from social life, often seeking extreme degrees of isolation and confinement because of various personal and social factors in their lives. The term hikikomori refers to both the sociological phenomenon in general as well as to people belonging to this societal group. Read more here.

Alice in Wonderland syndrome

Alice in Wonderland syndrome (AIWS, named after the novel written by Lewis Carroll), also known as Todd's syndrome[1], is a disorienting neurological condition which affects human perception. Sufferers may experience micropsia, macropsia, and/or size distortion of other sensory modalities. A temporary condition, it is often associated with migraines, brain tumors, and the use of psychoactive drugs.[citation needed] It can also present as the initial sign of the Epstein-Barr Virus (see mononucleosis). Anecdotal reports suggests that the symptoms of AIWS are fairly common in childhood[citation needed], with many people growing out of them in their teens. It appears that AIWS is also a common experience at sleep onset. Read more here.

Blaschko's lines

Blaschko's lines, also called the Lines of Blaschko, are skin lines invisible under normal conditions. (See the picture of the lines in external links). They become apparent when some diseases of the skin or mucosa manifest themselves according to these patterns. They follow a "V" shape over the back, "S" shaped whorls over the chest, stomach, and sides, and wavy shapes on the head.The lines are believed to trace the migration of embryonic cells.The stripes are a type of genetic mosaicism.They do not correspond to nervous, muscular, or lymphatic systems. The lines can be observed in other animals such as cats and dog. German dermatologist Alfred Blaschko is credited for the first demonstration of these lines in 1901.Read more here

Hypertrichosis

Hypertrichosis describes hair growth on the body in an amount which is considered abnormal.There are two distinct types of hypertrichosis: generalized hypertrichosis, which occurs over the entire body, and localized hypertrichosis, which is restricted to a certain area.[1] Hypertrichosis is either congenital (present at birth), or acquired later in life.The excess growth of hair occurs in areas of the skin with the exception of androgen-dependent hair of the pubic area, face, and axillary regions.Several circus sideshow performers in the 19th and early 20th centuries, such as Julia Pastrana, suffered from hypertrichosis.[6] They were usually displayed as "freaks" and promoted as having distinct human and animal traits. More extensive cases of hypertrichosis have been informally called werewolf syndrome. Read more here.

Progeria

rogeria (also known as "Hutchinson–Gilford progeria syndrome"and "Hutchinson–Gilford syndrome"is an extremely rare, severe, genetic condition wherein symptoms resembling aspects of aging are manifested at an early age. The disorder has a very low incidence and occurs in one per eight million live births.Those born with progeria typically live about thirteen years, although many have been known to live into their late teens and early twenties and rare individuals may even reach their forties. It is a genetic condition that occurs as a new mutation and is not usually inherited, although there is a uniquely inheritable form. This is in contrast to another rare but similar premature aging syndrome, dyskeratosis congenita (DKC), which is inheritable and will often be expressed multiple times in a family line.Scientists are particularly interested in progeria because it might reveal clues about the normal process of aging.Progeria was first described in 1886 by Jonathan Hutchinson[10] and also described independently in 1897 by Hastings Gilford.The condition was later named Hutchinson-Gilford Progeria syndrome (HGPS).Read more here

Pica

Pica is a medical disorder characterized by an appetite for substances largely non-nutritive (e.g. metal (coins, etc), clay, coal, soil, feces, chalk, paper, soap, mucus, ash, gum, etc.) or an abnormal appetite for some things that may be considered foods, such as food ingredients (e.g., flour, raw potato, raw rice, starch, ice cubes, salt).[1] In order for these actions to be considered pica, they must persist for more than one month at an age where eating such objects is considered developmentally inappropriate. The condition's name comes from the Latin word for magpie, a bird which is reputed to eat almost anything.[2] Pica is seen in all ages, particularly in pregnant women, small children, and those with developmental disabilities.Pica in children, while common, can be dangerous. Children eating painted plaster containing lead may suffer brain damage from lead poisoning. There is a similar risk from eating dirt near roads that existed prior to the phaseout of tetra-ethyl lead in gasoline (in some countries) or prior to the cessation of the use of contaminated oil (either used, or containing toxic PCBs or dioxin) to settle dust. In addition to poisoning, there is also a much greater risk of gastro-intestinal obstruction or tearing in the stomach.[citation needed] This is also true in animals. Another risk of dirt eating is the possible ingestion of animal feces and the accompanying parasites. Pica can also be found in animals, and is most commonly found in dogs.Read more here